Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Bacterial evolution in PCD and CF patients follows the same mutational steps.

Scientific reports - 28 Jun 2016

Sommer Lea M, Alanin Mikkel Christian, Marvig Rasmus L, Nielsen Kim Gjerum, Høiby Niels, von Buchwald Christian, Molin Søren, Johansen Helle Krogh

Abstract excerpt

Infections with Pseudomonas aeruginosa increase morbidity in primary ciliary dyskinesia (PCD) and cystic fibrosis (CF) patients. Both diseases are associated with a defect of the mucociliary clearance; in PCD caused by non-functional cilia, in CF by changed mucus. Whole genome sequencing of P. aeruginosa isolates from CF patients has shown that persistence of clonal lineages in the airways is facilitated by...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cystic Fibrosis
Share to Evolution, Molecular

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Genome, Bacterial

Share to Kartagener Syndrome

Share to Polymorphism, Single Nucleotide

Share to Pseudomonas aeruginosa

Share to Pseudomonas Infections

Source

Open in PubMed Open full text

Identifiers

PMID: 27349973
DOI: 10.1038/srep28732
PMCID: PMC4923847

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Bacterial evolution in PCD and CF patients follows the same mutational steps.PMID 27349973Read ↗

Long-Term Microevolution of Pseudomonas aeruginosa Differs between Mildly and Severely Affected Cystic Fibrosis LungsSemantic proximity Read ↗

Convergent evolution and adaptation of Pseudomonas aeruginosa within patients with cystic fibrosis.Semantic proximity Read ↗

Adaptive Evolution of Pseudomonas aeruginosa in Human Airways Shows Phenotypic Convergence Despite Diverse Patterns of Genomic Changes.Semantic proximity Read ↗

Pseudomonas aeruginosa Evolutionary Adaptation and Diversification in Cystic Fibrosis Chronic Lung Infections.Semantic proximity Read ↗

Microevolution of Pseudomonas aeruginosa in the airways of people with cystic fibrosis.Semantic proximity Read ↗

Pseudomonas aeruginosa Diversification during Infection Development in Cystic Fibrosis Lungs—A ReviewSemantic proximity Read ↗

Transmission and lineage displacement drive rapid population genomic flux in cystic fibrosis airway infections of a Pseudomonas aeruginosa epidemic strainSemantic proximity Read ↗

Pseudomonas aeruginosa infection and persistence mechanisms in cystic fibrosis patientsSemantic proximity Read ↗

Genome analysis of a transmissible lineage of pseudomonas aeruginosa reveals pathoadaptive mutations and distinct evolutionary paths of hypermutators.Semantic proximity Read ↗

Within-host microevolution of Pseudomonas aeruginosa in Italian cystic fibrosis patientsSemantic proximity Read ↗

Adaptive evolution of <i>P. aeruginosa</i> in human airways shows phenotypic convergence despite diverse patterns of genomic changesSemantic proximity Read ↗

Differential adaptation of microbial pathogens to airways of patients with cystic fibrosis and chronic obstructive pulmonary diseaseSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.