Article
Type 3 secretion system effector genotype and secretion phenotype of longitudinally collected Pseudomonas aeruginosa isolates from young children diagnosed with cystic fibrosis following newborn screening.
Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases - 1 Mar 2013
Hu H, Harmer C, Anuj S, Wainwright C E, Manos J, Cheney J, Harbour C, Zablotska I, Turnbull L, Whitchurch C B, Grimwood K, Rose B
Abstract excerpt
Studies of the type 3 secretion system (T3SS) in Pseudomonas aeruginosa isolates from chronically infected older children and adults with cystic fibrosis (CF) show a predominantly exoS+/exoU- (exoS+) genotype and loss of T3SS effector secretion over time. Relatively little is known about the role of the T3SS in the pathogenesis of early P. aeruginosa infection in the CF airway. In this longitudinal study, 168 P....
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.