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Article

Dynamic, morphotype-specific Candida albicans beta-glucan exposure during infection and drug treatment.

PLoS pathogens - 1 Dec 2008

Wheeler Robert T, Kombe Diana, Agarwala Sudeep D, Fink Gerald R

Abstract excerpt

Candida albicans, a clinically important dimorphic fungal pathogen that can evade immune attack by masking its cell wall beta-glucan from immune recognition, mutes protective host responses mediated by the Dectin-1 beta-glucan receptor on innate immune cells. Although the ability of C. albicans to switch between a yeast- or hyphal-form is a key virulence determinant, the role of each morphotype in beta-glucan...

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Identifiers

PMID: 19057660
DOI: 10.1371/journal.ppat.1000227
PMCID: PMC2587227

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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