Article
Effect of GSTM1 and GSTT1 double deletions in the development of oxidative stress in diabetic nephropathy patients.
Indian journal of biochemistry & biophysics - 1 Apr 2010
Datta Sudip K, Kumar Vivek, Ahmed Rafat S, Tripathi Ashok K, Kalra Om Prakash, Banerjee Basu Dev
Abstract excerpt
Association of diabetic nephropathy (DN) with the deletion of GSTT1 and GSTM1 genes is well reported. Oxidative stress (OS) has also been associated with the development of DN. The present study was conducted to find out, whether these deletions had any contributory role in the development of OS in patients with DN. Pre-dialysis venous blood samples were obtained from 60 patients with diabetic end-stage renal...
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