Article
Evidence for common short natural trans sense-antisense pairing between transcripts from protein coding genes.
Genome biology - 1 Jan 2008
Wang Ping, Yin Shanye, Zhang Zhenguo, Xin Dedong, Hu Landian, Kong Xiangyin, Hurst Laurence D
Abstract excerpt
BACKGROUND: There is increasing realization that regulation of genes is done partly at the RNA level by sense-antisense binding. Studies typically concentrate on the role of non-coding RNAs in regulating coding RNA. But the majority of transcripts in a cell are likely to be coding. Is it possible that coding RNA might regulate other coding RNA by short perfect sense-antisense binding? Here we compare all...
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