Article
Evidence for the regulation of alternative splicing via complementary DNA sequence repeats.
Bioinformatics (Oxford, England) - 15 Apr 2005
Lian Yun, Garner Harold R
Abstract excerpt
MOTIVATION: While the mechanism for regulating alternative splicing is poorly understood, secondary structure has been shown to be integral to this process. Due to their propensity for forming complementary hairpin loops and their elevated mutation rates, tandem repeated sequences have the potential to influence splicing regulation. RESULTS: An analysis of human intronic sequences reveals a strong correlation...
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