Article
The non-inherited maternal HLA haplotype affects the risk for type 1 diabetes.
International journal of immunogenetics - 1 Feb 2009
Akesson K, Carlsson A, Ivarsson S-A, Johansson C, Weidby B-M, Ludvigsson J, Gustavsson B, Lernmark A, Kockum I
Abstract excerpt
The aim was to test the hypothesis that the human leucocyte antigen (HLA) haplotype that is not inherited from the mother, that is, the non-inherited maternal antigen (NIMA) affects the risk for type 1 diabetes (T1D). A total of 563 children with T1D and 286 non-diabetic control children from Sweden were genotyped for DRB1, DQA1 and DQB1 alleles. The frequency of positively (DR4-DQA1*0301-B1*0302 and...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
