Article
Maternal microchimerism in peripheral blood in type 1 diabetes and pancreatic islet beta cell microchimerism.
Proceedings of the National Academy of Sciences of the United States of America - 30 Jan 2007
Nelson J Lee, Gillespie Kathleen M, Lambert Nathalie C, Stevens Anne M, Loubiere Laurence S, Rutledge Joe C, Leisenring Wendy M, Erickson Timothy D, Yan Zhen, Mullarkey Meghan E, Boespflug Nick D, Bingley Polly J, Gale Edwin A M
Abstract excerpt
Maternal cells have recently been found in the circulation and tissues of mothers' immune-competent children, including in adult life, and is referred to as maternal microchimerism (MMc). Whether MMc confers benefits during development or later in life or sometimes has adverse effects is unknown. Type 1 diabetes (T1D) is an autoimmune disease that primarily affects children and young adults. To identify and...
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