Article
[The genetic basis of suppression of tumors and metastases in Drosophila and man].
Zentralblatt fur Chirurgie - 1 Jan 1991
Gateff E
Abstract excerpt
The first causal relations between recessive gene mutation and malignancies were detected in a fly (Drosophila melanogaster). This is a recessive-lethal heredity. Tumour suppression was demonstrated in mouse cell hybrids in the late sixties. Tumour suppressor antigens are developed recently for W...
Topics
- Animals
- Drosophila melanogaster
- Genes, Lethal
- Genes, Recessive
- Genes, Tumor Suppressor
- Humans
- Mutation
- Neoplasm Metastasis
- Neoplasms
- Neoplasms, Experimental