Article
Predictors of the scleroderma phenotype in fibroblasts from systemic sclerosis patients.
Journal of the European Academy of Dermatology and Venereology : JEADV - 1 Feb 2009
Qi Q, Guo Q, Tan G, Mao Y, Tang H, Zhou C, Zeng F
Abstract excerpt
BACKGROUND: Fibroblasts from skin lesions generally exhibit the scleroderma phenotype in the early stage of in vitro culture, and act as one of the most important samples to investigate systemic sclerosis. However, not all cell lines from patients show the scleroderma phenotype, and little prospective evidence can be relied on to predict the phenotype of fibroblasts from systemic sclerosis patients. OBJECTIVE:...
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