Article
A global view of antibiotic resistance.
FEMS microbiology reviews - 1 Jan 2009
Martinez Jose Luis, Fajardo Alicia, Garmendia Leonor, Hernandez Alvaro, Linares Juan Francisco, Martínez-Solano Laura, Sánchez María Blanca
Abstract excerpt
Antibiotic resistance is one of the few examples of evolution that can be addressed experimentally. The present review analyses this resistance, focusing on the networks that regulate its acquisition and its effect on bacterial physiology. It is widely accepted that antibiotics and antibiotic resistance genes play fundamental ecological roles - as weapons and shields, respectively - in shaping the structures of...
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