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Article

Pharmacokinetic study of the variability of indinavir drug levels when boosted with ritonavir in HIV-infected children.

Pharmacology - 1 Jan 2009

Curras Verónica, Hocht Christian, Mangano Andrea, Niselman Viviana, Mariño Hernández Eduardo, Cáceres Guido Paulo, Mecikovsky Débora, Bellusci Carolina, Bologna Rosa, Sen Luisa, Rubio Modesto C, Bramuglia Guillermo F

Abstract excerpt

The aim of this work is to: (1) assess therapeutic drug monitoring of indinavir (IDV) during clinical routine practice in HIV-infected children, whose antiretroviral treatment includes IDV boosted with ritonavir (RTV), and (2) describe a possible relationship between IDV pharmacokinetics and MDR1 genotypes. In 21 ambulatory pediatric patients receiving IDV plus RTV, IDV plasma levels and MDR1 genotypes on exon 26...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 19052483
DOI: 10.1159/000178813

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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