Article
Population Pharmacokinetics and Pharmacogenetics Analysis of Rilpivirine in HIV-1-Infected Individuals.
Antimicrobial agents and chemotherapy - 1 Jan 2017
Aouri Manel, Barcelo Catalina, Guidi Monia, Rotger Margalida, Cavassini Matthias, Hizrel Cédric, Buclin Thierry, Decosterd Laurent A, Csajka Chantal
Abstract excerpt
Rilpivirine (RPV), the latest nonnucleoside reverse transcriptase inhibitor active against HIV-1, is prescribed in a standard dosage of 25 mg once a day in combination with emtricitabine (FTC) and tenofovir disoproxil fumarate (TDF). The aim of this observational study was to characterize the RPV pharmacokinetic profile, to quantify interpatient variability, and to identify potential factors that could influence...
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