Article
Influence of pharmacogenetics on indinavir disposition and short-term response in HIV patients initiating HAART.
European journal of clinical pharmacology - 1 Jul 2009
Bertrand Julie, Treluyer Jean-Marc, Panhard Xavière, Tran Agnes, Auleley Solange, Rey Elisabeth, Salmon-Céron Dominique, Duval Xavier, Mentré France
Abstract excerpt
AIMS: To assess the relationship between genetic polymorphisms and indinavir pharmacokinetic variability and to study the link between concentrations and short-term response or metabolic safety. METHODS: Forty protease inhibitor-naive patients initiating highly active antiretroviral therapy (HAAR...
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