Article
Characterization and classification of zebrafish brain morphology mutants.
Anatomical record (Hoboken, N.J. : 2007) - 1 Jan 2009
Lowery Laura Anne, De Rienzo Gianluca, Gutzman Jennifer H, Sive Hazel
Abstract excerpt
The mechanisms by which the vertebrate brain achieves its three-dimensional structure are clearly complex, requiring the functions of many genes. Using the zebrafish as a model, we have begun to define genes required for brain morphogenesis, including brain ventricle formation, by studying 16 mutants previously identified as having embryonic brain morphology defects. We report the phenotypic characterization of...
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