Article
Identification of zebrafish insertional mutants with defects in visual system development and function.
Genetics - 1 May 2005
Gross Jeffrey M, Perkins Brian D, Amsterdam Adam, Egaña Ana, Darland Tristan, Matsui Jonathan I, Sciascia Salvatore, Hopkins Nancy, Dowling John E
Abstract excerpt
Genetic analysis in zebrafish has been instrumental in identifying genes necessary for visual system development and function. Recently, a large-scale retroviral insertional mutagenesis screen, in which 315 different genes were mutated, that resulted in obvious phenotypic defects by 5 days postfertilization was completed. That the disrupted gene has been identified in each of these mutants provides unique...
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