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Article

Leptin expression correlates with favorable clinicopathologic phenotype and better prognosis in colorectal adenocarcinoma.

Annals of surgical oncology - 1 Feb 2009

Paik Seung Sam, Jang Se-Min, Jang Ki-Seok, Lee Kang Hong, Choi Dongho, Jang Se Jin

Abstract excerpt

Leptin, the product of the ob gene, is an adipocyte-derived neurohormone that regulates body fat storage and feeding behavior. Some studies have suggested that leptin has growth-factor-like functions in epithelial cells and its abnormal expression may be involved in cancer development and progression. We investigated leptin expression in normal and neoplastic colorectal tissues and its association with...

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Identifiers

PMID: 19050975
DOI: 10.1245/s10434-008-0221-7

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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