Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

ACE insertion/deletion, but not -240A>T polymorphism, modulates the severity in heart failure.

Journal of investigative medicine : the official publication of the American Federation for Clinical Research - 1 Dec 2008

Fatini Cinzia, Sticchi Elena, Marcucci Rossella, Said Abdihakim Abdullahi, Del Pace Stefano, Verdiani Valerio, Nozzoli Carlo, Gensini Gian Franco, Abbate Rosanna

Abstract excerpt

OBJECTIVE: : ACE gene is reported to be a candidate gene in heart failure. The insertion/deletion (I/D) polymorphism has been observed to be a predictor of mortality in this disease, but no data are available concerning the role of ACE -240A>T polymorphism. In this study, we investigated the role of ACE I/D and -240A>T polymorphisms in influencing both severity and clinical outcomes in patients with heart...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Aged
Share to Gene Deletion

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Heart Failure

Share to Mutagenesis, Insertional

Share to Natriuretic Peptide, Brain

Share to Peptide Fragments

Share to Peptidyl-Dipeptidase A

Share to Polymorphism, Genetic

Source

Identifiers

PMID: 19050458
DOI: 10.2310/JIM.0b013e31818e8028

Genes

ACE

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

ACE insertion/deletion, but not -240A>T polymorphism, modulates the severity in heart failure.PMID 19050458Read ↗

Angiotensin-converting-enzyme gene polymorphism and heart failure: a case-control study.Semantic proximity Read ↗

Correlation between the insertion-deletion variant of the angiotensin-converting enzyme gene and various classes of heart failure.Semantic proximity Read ↗

Pharmacogenetic interactions between beta-blocker therapy and the angiotensin-converting enzyme deletion polymorphism in patients with congestive heart failure.Semantic proximity Read ↗

Angiotensin-converting enzyme gene polymorphism interacts with left ventricular ejection fraction and brain natriuretic peptide levels to predict mortality after myocardial infarction.Semantic proximity Read ↗

Hypothesis: an angiotensin converting enzyme genotype, present in one in three caucasians, is associated with increased mortality rate.Semantic proximity Read ↗

ACE-Inhibition Benefit on Lung Function in Heart Failure is Modulated by ACE Insertion/Deletion Polymorphism.Semantic proximity Read ↗

Angiotensin converting enzyme insertion/deletion polymorphism and the risk of heart failure in hypertensive subjects.Semantic proximity Read ↗

Influence of gene polymorphisms of the renin-angiotensin system on clinical outcome in heart failure among the Chinese.Semantic proximity Read ↗

Influence of Insertion/Deletion Polymorphism of the Angiotensin Converting Enzyme Gene on Adiposity and Cardiac Function in Patients with Heart Failure.Semantic proximity Read ↗

[Pharmacogenomic control of angiotensin converting enzyme gene I/D polymorphism predominant risk factor of development of chronic heart failure and target of enalapril treatment].Semantic proximity Read ↗

Deletion polymorphism of the angiotensin I-converting enzyme gene in elderly patients with coronary heart disease.Semantic proximity Read ↗

Relationship between ACE gene polymorphism and ischemic chronic heart failure in Turkish population.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.