Influence of Insertion/Deletion Polymorphism of the Angiotensin Converting Enzyme Gene on Adiposity and Cardiac Function in Patients with Heart Failure.

doi:10.36660/abc.20240204

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Influence of Insertion/Deletion Polymorphism of the Angiotensin Converting Enzyme Gene on Adiposity and Cardiac Function in Patients with Heart Failure.

Arquivos brasileiros de cardiologia - 1 Jan 2025

Vale Marla Darlene Machado, Ribeiro Édina Caroline Ternus, Knobloch Ingrid da Silveira, Schwartz Ida Vanessa Doederlein, Sperb-Ludwig Fernanda, Souza Gabriela Corrêa

Abstract excerpt

BACKGROUND: The angiotensin-converting enzyme (ACE) insertion/deletion (I/D) polymorphism (rs4340) is associated with the pathogenesis of heart failure (HF). This polymorphism may contribute to a greater propensity for severe HF and excess weight. OBJECTIVE: To evaluate adiposity, cardiac function, and their association with ACE I/D polymorphism in HF patients. METHODS: Cross-sectional study with ambulatory...

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PMID: 39841754
DOI: 10.36660/abc.20240204
PMCID: PMC11841369

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