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Article

ACE-Inhibition Benefit on Lung Function in Heart Failure is Modulated by ACE Insertion/Deletion Polymorphism.

Cardiovascular drugs and therapy - 1 Apr 2016

Contini Mauro, Compagnino Elisa, Cattadori Gaia, Magrì Damiano, Camera Marina, Apostolo Anna, Farina Stefania, Palermo Pietro, Gertow Karl, Tremoli Elena, Fiorentini Cesare, Agostoni Piergiuseppe

Abstract excerpt

PURPOSE: The benefit of angiotensin converting enzyme (ACE) inhibition in chronic heart failure (HF) is partially due to its effects on pulmonary function and particularly on lung diffusion, the latter being counteracted by acetylsalicylic acid (ASA). Tissue ACE activity is largely determined by an insertion/deletion (I/D) polymorphism resulting in three possible genotypes (DD, ID and II). It is not clear if ACE...

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PMID: 26847573
DOI: 10.1007/s10557-016-6645-6

Genes

ACE

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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