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Abl depletion via autophagy mediates the beneficial effects of quercetin against Alzheimer pathology across species

14 Oct 2023

Abstract excerpt

Alzheimer's disease is the most common age-associated neurodegenerative disorder and the most frequent form of dementia in our society. Aging is a complex biological process concurrently shaped by genetic, dietary and environmental factors and natural compounds are emerging for their beneficial effects against age-related disorders. Besides their antioxidant activity often described in simple model organisms, the...

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PMID: 37838776
DOI: 10.1038/s41420-023-01592-x

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