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Article

Structural and thermodynamic studies of Bergerac-SH3 chimeras.

Biophysical chemistry - 1 Feb 2009

Gushchina Liubov' V, Gabdulkhakov Azat G, Nikonov Stanislav V, Mateo Pedro L, Filimonov Vladimir V

Abstract excerpt

Bergerac-type chimeras of spectrin SH3 were designed by extending a beta-hairpin by eight amino acids so that the extension protruded from the domain body like a "nose" being exposed to the solvent. A calorimetric study of several Bergerac-SH3 variants was carried out over a wide range of pH values and protein concentrations and the three-dimensional structure of one of them, SHH, was determined. X-ray studies...

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Source

Identifiers

PMID: 19042078
DOI: 10.1016/j.bpc.2008.10.011

Genes

SHH

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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