Article
Chromosome alignment and transvection are antagonized by condensin II.
Science (New York, N.Y.) - 28 Nov 2008
Hartl Tom A, Smith Helen F, Bosco Giovanni
Abstract excerpt
Polytene chromosome structure is a characteristic of some polyploid cells where several to thousands of chromatids are closely associated with perfect alignment of homologous DNA sequences. Here, we show that Drosophila condensin II promotes disassembly of polytene structure into chromosomal components. Condensin II also negatively regulates transvection, a process whereby certain alleles are influenced...
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