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Article

Implication of complex vertebral malformation and bovine leukocyte adhesion deficiency DNA-based testing on disease frequency in the Holstein population.

Journal of dairy science - 1 Dec 2008

Schütz E, Scharfenstein M, Brenig B

Abstract excerpt

Two inherited lethal disorders, bovine leukocyte adhesion deficiency (BLAD) and complex vertebral malformation (CVM), play a major role in breeding of Holstein cattle. Both inherited diseases are based on single nucleotide polymorphisms that have been known for 12 and 7 yr, respectively. A total of 25,753 cattle were genotyped for BLAD (18,200 tests) and CVM (14,493 tests) in our laboratory since the beginning of...

Topics

Animals
Breeding
Cattle
Cattle Diseases
Female
Gene Frequency
Leukocyte-Adhesion Deficiency Syndrome
Male
Mutation
Polymorphism, Single Nucleotide
Prevalence

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Selection, Genetic

Spinal Diseases

Source

Identifiers

PMID: 19038961
DOI: 10.3168/jds.2008-1154

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