Article
Association of the ACTN3 genotype and physical functioning with age in older adults.
The journals of gerontology. Series A, Biological sciences and medical sciences - 1 Nov 2008
Delmonico Matthew J, Zmuda Joseph M, Taylor Brent C, Cauley Jane A, Harris Tamara B, Manini Todd M, Schwartz Ann, Li Rongling, Roth Stephen M, Hurley Ben F, Bauer Douglas C, Ferrell Robert E, Newman Anne B
Abstract excerpt
OBJECTIVE: The purpose of this study was to examine the association of the alpha-actinin-3 (ACTN3) R577X polymorphism on muscle function and physical performance in older adults. METHODS: We measured knee extensor torque, midthigh muscle cross-sectional area, muscle quality, short physical performance battery score, and 400-meter walk time at baseline and after 5 years in white older adults aged 70-79 years in...
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