Article
The effect of BDNF gene variants on asthma in German children.
Allergy - 1 Dec 2009
Zeilinger S, Pinto L A, Nockher W A, Depner M, Klopp N, Illig T, von Mutius E, Renz H, Kabesch M
Abstract excerpt
BACKGROUND: Allergic inflammation can trigger neuronal dysfunction and structural changes in the airways and the skin. Levels of brain-derived neurotrophic factor (BDNF) are strongly up regulated at the location of allergic inflammation. AIM: We systematically investigated whether polymorphisms in the BDNF gene influence the development or severity of asthma and atopic diseases. METHODS: The BDNF gene was...
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