Article
The association of SNPs in ADIPOQ, ADIPOR1, and ADIPOR2 with insulin sensitivity in a cohort of adolescents and their parents.
Human genetics - 1 Feb 2009
Rasmussen-Torvik Laura J, Pankow James S, Jacobs David R, Steinberger Julia, Moran Antoinette, Sinaiko Alan R
Abstract excerpt
Few studies have examined the association of SNPs in the adiponectin (ADIPOQ) and adiponectin receptor 1 and 2 (ADIPOR1, ADIPOR2) genes with the euglycemic clamp, i.e. the gold standard measure of insulin sensitivity. The association of comprehensive tag SNPs in these genes with insulin sensitivity was examined in a cohort of adolescents and their parents. Probands and siblings (n=441, mean age=17.9 years) were...
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