Article
Genetic and systems level analysis of Drosophila sticky/citron kinase and dFmr1 mutants reveals common regulation of genetic networks.
BMC systems biology - 25 Nov 2008
Bauer Christopher R, Epstein Andrew M, Sweeney Sarah J, Zarnescu Daniela C, Bosco Giovanni
Abstract excerpt
BACKGROUND: In Drosophila, the genes sticky and dFmr1 have both been shown to regulate cytoskeletal dynamics and chromatin structure. These genes also genetically interact with Argonaute family microRNA regulators. Furthermore, in mammalian systems, both genes have been implicated in neuronal development. Given these genetic and functional similarities, we tested Drosophila sticky and dFmr1 for a genetic...
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