Article
Polymorphisms of the DNA repair genes XRCC1 and XRCC3 and risk of lung and colorectal cancer: a case-control study in a Southern Italian population.
Anticancer research - 1 Jan 2000
Improta Giuseppina, Sgambato Alessandro, Bianchino Gabriella, Zupa Angela, Grieco Vitina, La Torre Giuseppe, Traficante Antonio, Cittadini Achille
Abstract excerpt
BACKGROUND: Genetic polymorphisms in DNA repair genes may influence individual variation in DNA repair capacity, which may be associated with a higher risk of developing cancer. Studies on the association between DNA repair gene polymorphisms and lung and colorectal cancer risk appear to be very limited. This study was designed to examine the polymorphisms associated with two DNA repair genes, namely XRCC1...
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