Article
Association of DNA repair gene XRCC1 and lung cancer susceptibility among nonsmoking Chinese women.
Cancer genetics and cytogenetics - 1 Jan 2009
Yin Jiaoyang, Vogel Ulla, Ma Yegang, Qi Rong, Wang Huiwen
Abstract excerpt
Nonsmokers who develop lung cancer provide a good model for investigating the effect of genetic polymorphisms. XRCC1 is one of the major DNA repair proteins involved in the base-excision repair pathway. XRCC1 gene variations may lead to lower DNA repair capacity and thus confer inherited predisposition to cancer risk. To address this question in more detail, we conducted a hospital-based case-control study...
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