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Article

The association of the DNA repair gene XRCC3 Thr241Met polymorphism with susceptibility to colorectal cancer in a Chinese population.

Cancer genetics and cytogenetics - 1 Nov 2005

Jin Ming-Juan, Chen Kun, Song Liang, Fan Chun-Hong, Chen Qing, Zhu Yi-Min, Ma Xin-Yuan, Yao Kai-Yan

Abstract excerpt

Growing evidence suggests that the Thr241Met (T241M) polymorphism in the homologous recombination repair gene XRCC3 may alter DNA repair capacity and subsequent susceptibility to carcinogens. In a few studies of colorectal cancer (CRC), however, the results have been discrepant. A population-based nested case-control study including 140 cases and 280 cancer-free controls was conducted to evaluate the effect of...

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Source

Identifiers

PMID: 16271954
DOI: 10.1016/j.cancergencyto.2005.05.001

Genes

XRCC3

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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