Article
XRCC1 polymorphism and lung cancer risk.
Expert review of molecular diagnostics - 1 Nov 2008
Schneider Joachim, Classen Vera, Helmig Simone
Abstract excerpt
DNA repair plays a critical role in protecting the genome of the cell from the insults of carcinogens or ionizing radiation. Reduced DNA repair capacity can increase the susceptibility to environmental- or occupational-induced cancers. Three coding polymorphisms at codon 194, codon 280 and codon...
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