The ecdysone-inducible Broad-complex and E74 early genes interact to regulate target gene transcription and Drosophila metamorphosis.

doi:10.1093/genetics/141.3.1025

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Article

The ecdysone-inducible Broad-complex and E74 early genes interact to regulate target gene transcription and Drosophila metamorphosis.

Genetics - 1 Nov 1995

Fletcher J C, Thummel C S

Abstract excerpt

Pulses of the steroid hormone ecdysone initiate Drosophila metamorphosis by inducing widespread changes in gene expression. The Broad-Complex (BR-C) and E74 are induced directly by ecdysone and encode families of transcription factors that regulate ecdysone primary- and secondary-response genes....

Topics

Alleles
Animals
DNA-Binding Proteins
Drosophila Proteins
Drosophila melanogaster
Ecdysone
Gene Expression Regulation, Developmental
Genes, Insect
Genetic Complementation Test
Glue Proteins, Drosophila
Larva
Metamorphosis, Biological

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Multigene Family

Phenotype

Transcription Factors

Transcription, Genetic

Transcriptional Activation

Zinc Fingers

Source

Open in PubMed Open full text

Identifiers

PMID: 8582609
DOI: 10.1093/genetics/141.3.1025
PMCID: PMC1206826

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-8582609-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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The ecdysone-inducible Broad-complex and E74 early genes interact to regulate target gene transcription and Drosophila metamorphosis.PMID 8582609Read ↗

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