Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Anciently duplicated Broad Complex exons have distinct temporal functions during tissue morphogenesis.

Development genes and evolution - 1 Jul 2007

Spokony Rebecca F, Restifo Linda L

Abstract excerpt

Broad Complex (BRC) is an essential ecdysone-pathway gene required for entry into and progression through metamorphosis in Drosophila melanogaster. Mutations of three BRC complementation groups cause numerous phenotypes, including a common suite of morphogenesis defects involving central nervous system (CNS), adult salivary glands (aSG), and male genitalia. These defects are phenocopied by the juvenile hormone...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Animals, Genetically Modified
Share to Central Nervous System

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Drosophila

Share to Drosophila Proteins

Share to Genes, Insect

Share to Morphogenesis

Share to Protein Isoforms

Share to Salivary Glands

Source

Identifiers

PMID: 17530286
DOI: 10.1007/s00427-007-0159-y

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Anciently duplicated Broad Complex exons have distinct temporal functions during tissue morphogenesis.PMID 17530286Read ↗

Relationships between protein isoforms and genetic functions demonstrate functional redundancy at the Broad-Complex during Drosophila metamorphosis.Semantic proximity Read ↗

Dynamic expression of broad-complex isoforms mediates temporal control of an ecdysteroid target gene at the onset of Drosophila metamorphosis.Semantic proximity Read ↗

A juvenile hormone agonist reveals distinct developmental pathways mediated by ecdysone-inducible broad complex transcription factors.Semantic proximity Read ↗

The steroid hormone-regulated gene Broad Complex is required for dendritic growth of motoneurons during metamorphosis of Drosophila.Semantic proximity Read ↗

The bric à brac locus consists of two paralogous genes encoding BTB/POZ domain proteins and acts as a homeotic and morphogenetic regulator of imaginal development in Drosophila.Semantic proximity Read ↗

Antagonistic role of the BTB-zinc finger transcription factors Chinmo and Broad-Complex in the juvenile/pupal transition and in growth controlSemantic proximity Read ↗

The Drosophila Broad-Complex plays a key role in controlling ecdysone-regulated gene expression at the onset of metamorphosis.Semantic proximity Read ↗

The role of Broad in the development of Tribolium castaneum: implications for the evolution of the holometabolous insect pupa.Semantic proximity Read ↗

C. elegans CPB-3 interacts with DAZ-1 and functions in multiple steps of germline developmentSemantic proximity Read ↗

Control of Dopa decarboxylase gene expression by the Broad-Complex during metamorphosis in Drosophila.Semantic proximity Read ↗

The ecdysone-inducible Broad-complex and E74 early genes interact to regulate target gene transcription and Drosophila metamorphosis.Semantic proximity Read ↗

The Drosophila BTB domain protein Jim Lovell has roles in multiple larval and adult behaviors.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.