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Article

Peripheral B cell abnormalities and disease activity in systemic lupus erythematosus

24 Nov 2008

Abstract excerpt

Autoreactive B cells and plasma cells appear to be of central importance in the pathogenesis of systemic lupus erythematosus (SLE) characterized by a plethora of autoantibodies. Recent insights into abnormalities of B cell and plasma cell compartments in human SLE have identified a number of cellular disturbances within these compartments that in part correlate with the disease activity. This review discusses...

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PMID: 19029273
DOI: 10.1177/0961203308095138

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