Article
T-cell and B-cell function in lupus.
Current opinion in rheumatology - 1 Oct 1992
Via C S, Handwerger B S
Abstract excerpt
B-cell hyperactivity is characteristic of lupus and appears to be, in many instances, T-cell driven. Recent work continues to examine the paradox of T-cell activation in vivo and depressed T-cell function in vitro. The role of intrinsic B-cell abnormalities, particularly in CD5+ B cells, is an ar...
Topics
- Animals
- Antigens, CD
- B-Lymphocytes
- CD5 Antigens
- Cytokines
- Humans
- Lupus Erythematosus, Systemic
- Mice
- Phenotype
- Receptors, Antigen, T-Cell
- T-Lymphocytes