Genetic variation in the GDF5 region is associated with osteoarthritis, height, hip axis length and fracture risk: the Rotterdam study.

doi:10.1136/ard.2008.099655

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Article

Genetic variation in the GDF5 region is associated with osteoarthritis, height, hip axis length and fracture risk: the Rotterdam study.

Annals of the rheumatic diseases - 1 Nov 2009

Vaes R B A, Rivadeneira F, Kerkhof J M, Hofman A, Pols H A P, Uitterlinden A G, van Meurs J B J

Abstract excerpt

BACKGROUND: A polymorphism (rs143383; T to C) near the GDF5 gene has been associated with height and osteoarthritis (OA), but debate exists about whether its primary biological action is directed to cartilage or bone. OBJECTIVE: To study the association between genetic variation in the GDF5 region and radiographic osteoarthritis (ROA) susceptibility, height, bone size parameters and fracture risk in a large...

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Identifiers

PMID: 19029166
DOI: 10.1136/ard.2008.099655

Genes

GDF5
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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

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Genetic variation in the GDF5 region is associated with osteoarthritis, height, hip axis length and fracture risk: the Rotterdam study.PMID 19029166Read ↗

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