Article
Bipotent progenitors as embryonic origin of retinal stem cells.
The Journal of cell biology - 5 Jun 2017
Tang Xia, Gao Jianan, Jia Xinling, Zhao Wencao, Zhang Yijie, Pan Weijun, He Jie
Abstract excerpt
In lower vertebrates, retinal stem cells (RSCs) capable of producing all retinal cell types are a resource for retinal tissue growth throughout life. However, the embryonic origin of RSCs remains largely elusive. Using a Zebrabow-based clonal analysis, we characterized the RSC niche in the ciliary marginal zone of zebrafish retina and illustrate that blood vessels associated with RSCs are required for the...
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