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Article

CD133+adult human retinal cells remain undifferentiated in Leukaemia Inhibitory Factor (LIF)

23 Feb 2009

Abstract excerpt

BACKGROUND: CD133 is a cell surface marker of haematopoietic stem and progenitor cells. Leukaemia inhibitory factor (LIF), sustains proliferation and not differentiation of embryonic stem cells. We used CD133 to purify adult human retinal cells and aimed to determine what effect LIF had on these cultures and whether they still had the ability to generate neurospheres. METHODS: Retinal cell suspensions were...

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PMID: 19236693
DOI: 10.1186/1471-2415-9-1

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