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Article

Current concepts of blood-brain barrier development.

The International journal of developmental biology - 1 Jan 2011

Liebner Stefan, Czupalla Cathrin J, Wolburg Hartwig

Abstract excerpt

Homeostasis of the central nervous system (CNS) microenvironment is essential for its normal function and is maintained by the blood-brain barrier (BBB). The BBB proper is made up of endothelial cells (ECs) interconnected by tight junctions (TJs) that reveal a unique morphology and biochemical composition of the body's vasculature. In this article, we focus on developmental aspects of the BBB and describe...

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Identifiers

PMID: 21769778
DOI: 10.1387/ijdb.103224sl

Genes

AQP4

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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