Article
Genetics of susceptibility to malaria related phenotypes.
Infection, genetics and evolution : journal of molecular epidemiology and evolutionary genetics in infectious diseases - 1 Jan 2009
Carpenter Danielle, Rooth Ingegerd, Färnert Anna, Abushama Hind, Quinnell Rupert J, Shaw Marie-Anne
Abstract excerpt
Previous studies have established a genetic component for susceptibility to malaria. Here we use a pedigree based approach, and transmission disequilibrium testing (TDT), to identify immune response genes that influence susceptibility to Plasmodium falciparum malarial phenotypes (parasite density and frequency of clinical episodes) in a Tanzanian population. Evidence for association was observed between markers...
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