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Article

Assessing the combined impact of 18 common genetic variants of modest effect sizes on type 2 diabetes risk.

Diabetes - 1 Nov 2008

Lango Hana, Palmer Colin N A, Morris Andrew D, Zeggini Eleftheria, Hattersley Andrew T, McCarthy Mark I, Frayling Timothy M, Weedon Michael N

Abstract excerpt

OBJECTIVES: Genome-wide association studies have dramatically increased the number of common genetic variants that are robustly associated with type 2 diabetes. A possible clinical use of this information is to identify individuals at high risk of developing the disease, so that preventative measures may be more effectively targeted. Here, we assess the ability of 18 confirmed type 2 diabetes variants to...

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Identifiers

PMID: 18591388
DOI: 10.2337/db08-0504
PMCID: PMC2570411

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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