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Article

Neuronal death resulting from targeted disruption of the Snf2 protein ATRX is mediated by p53.

The Journal of neuroscience : the official journal of the Society for Neuroscience - 19 Nov 2008

Seah Claudia, Levy Michael A, Jiang Yan, Mokhtarzada Sulayman, Higgs Douglas R, Gibbons Richard J, Bérubé Nathalie G

Abstract excerpt

ATRX, a chromatin remodeling protein of the Snf2 family, participates in diverse cellular functions including regulation of gene expression and chromosome alignment during mitosis and meiosis. Mutations in the human gene cause alpha thalassemia mental retardation, X-linked (ATR-X) syndrome, a rare disorder characterized by severe cognitive deficits, microcephaly and epileptic seizures. Conditional inactivation of...

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Identifiers

PMID: 19020049
DOI: 10.1523/JNEUROSCI.4048-08.2008
PMCID: PMC6671724

Genes

ATRX
ATR

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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Neuronal death resulting from targeted disruption of the Snf2 protein ATRX is mediated by p53.PMID 19020049Read ↗

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ATRX, a guardian of chromatinSemantic proximity Read ↗

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