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Article

1513A>C polymorphism in the P2X7 receptor gene in patients with papillary thyroid cancer: correlation with histological variants and clinical parameters.

The Journal of clinical endocrinology and metabolism - 1 Feb 2009

Dardano Angela, Falzoni Simonetta, Caraccio Nadia, Polini Antonio, Tognini Sara, Solini Anna, Berti Piero, Di Virgilio Francesco, Monzani Fabio

Abstract excerpt

INTRODUCTION: The modulation of the purinergic receptor P2X7 may be implicated in human carcinogenesis. The 1513A>C and 489C>T polymorphisms of P2X7R gene induce loss of function and gain of function, respectively. AIM: The aim of the study was to assess the frequency of both 1513A>C and 489C>T polymorphisms in patients with papillary thyroid carcinoma (PTC) and to evaluate the possible association with clinical...

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Identifiers

PMID: 19017759
DOI: 10.1210/jc.2008-1322

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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