Article
Persistence of type-specific human papillomavirus infection and increased long-term risk of cervical cancer.
Journal of the National Cancer Institute - 21 Sept 2011
Chen Hui-Chi, Schiffman Mark, Lin Ching-Yu, Pan Mei-Hung, You San-Lin, Chuang Li-Chung, Hsieh Chang-Yao, Liaw Kai-Li, Hsing Ann W, Chen Chien-Jen
Abstract excerpt
BACKGROUND: Human papillomavirus (HPV) persistence is the pivotal event in cervical carcinogenesis. We followed a large-scale community-based cohort for 16 years to investigate the role of genotype-specific HPV persistence in predicting cervical cancer including invasive and in situ carcinoma. METHODS: At the baseline examination in 1991-1992, 11,923 participants (aged 30-65 years) consented to HPV testing and...
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