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Article

Rare occurrence of PHOX2b mutations in sporadic neuroblastomas.

Journal of pediatric hematology/oncology - 1 Oct 2008

Serra Alexandre, Häberle Beate, König Inke R, Kappler Roland, Suttorp Meinolf, Schackert Hans K, Roesner Dietmar, Fitze Guido

Abstract excerpt

Neuroblastomas (NBs) are frequent solid tumors in childhood for which no specific genetic marker linked to their development has been identified to date. PHOX2b, which regulates the autonomic neuron development, has been associated with the development of autonomic diseases, and has been considered a potential candidate gene for neural crest-derived tumors such as NB. To ascertain the role of the PHOX2b gene in...

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PMID: 19011468
DOI: 10.1097/MPH.0b013e3181772141

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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