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Article

Clinical relevance and prevalence of polymorphisms in CYP3A5 and MDR1 genes that encode tacrolimus biotransformation enzymes in liver transplant recipients.

Transplantation proceedings - 1 Nov 2008

Barrera-Pulido L, Aguilera-García I, Docobo-Pérez F, Alamo-Martínez J M, Pareja-Ciuró F, Nuñez-Roldán A, Gómez-Bravo M A, Bernardos-Rodríguez A

Abstract excerpt

OBJECTIVES: To study the prevalence and clinical significance of polymorphisms in the CYP3A5 and MDR1 genes in liver transplant patients and their donors; to determine the relative importance of genes from the donor and the recipient; to assess the relationship of polymorphisms with the variability of concentration/dose of tacrolimus for optimization and individualization regimens. MATERIALS AND METHODS: This...

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Identifiers

PMID: 19010156
DOI: 10.1016/j.transproceed.2008.09.016

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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