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Article

Zebrafish Tsc1 reveals functional interactions between the cilium and the TOR pathway.

Human molecular genetics - 15 Feb 2009

DiBella Linda M, Park Alice, Sun Zhaoxia

Abstract excerpt

The cell surface organelle called the cilium is essential for preventing kidney cyst formation and for establishing left-right asymmetry of the vertebrate body plan. Recent advances suggest that the cilium functions as a sensory organelle in vertebrate cells for multiple signaling pathways such as the hedgehog and the Wnt pathways. Prompted by kidney cyst formation in tuberous sclerosis complex (TSC) patients and...

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Source

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Identifiers

PMID: 19008302
DOI: 10.1093/hmg/ddn384
PMCID: PMC2722215

Genes

TSC1
TSC2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Zebrafish Tsc1 reveals functional interactions between the cilium and the TOR pathway.PMID 19008302Read ↗

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