Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

All along the watchtower: is the cilium a tumor suppressor organelle?

Biochimica et biophysica acta - 1 Dec 2008

Mans Dorus A, Voest Emile E, Giles Rachel H

Abstract excerpt

Cilia or flagella have been around since almost the beginning of life, and have now developed specialized cell-type specific functions from locomotion to acting as environmental sensors participating in cell signalling. Genetic defects affecting cilia result in a myriad of pathological instances, including infertility, obesity, blindness, deafness, skeletal malformations, and lung problems. However, the...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cell Cycle
Share to Cilia
Share to Hedgehog Proteins

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Kidney Neoplasms

Share to Sensory Receptor Cells

Share to von Hippel-Lindau Disease

Share to Von Hippel-Lindau Tumor Suppressor Protein

Share to Wnt Proteins

Source

Identifiers

PMID: 18343234
DOI: 10.1016/j.bbcan.2008.02.002

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

All along the watchtower: is the cilium a tumor suppressor organelle?PMID 18343234Read ↗

The nonmotile ciliopathies.Semantic proximity Read ↗

Ciliopathies: an expanding disease spectrum.Semantic proximity Read ↗

The primary cilium as a cellular signaling center: lessons from disease.Semantic proximity Read ↗

Motile and non-motile cilia in human pathology: from function to phenotypes.Semantic proximity Read ↗

Primary cilia and signaling pathways in mammalian development, health and disease.Semantic proximity Read ↗

Making sense of cilia in disease: the human ciliopathies.Semantic proximity Read ↗

The ciliopathies: an emerging class of human genetic disorders.Semantic proximity Read ↗

Antennas of organ morphogenesis: the roles of cilia in vertebrate kidney developmentSemantic proximity Read ↗

Cilia, adenomatous polyposis coli and associated diseases.Semantic proximity Read ↗

Cilia and centrosomes: a unifying pathogenic concept for cystic kidney disease?Semantic proximity Read ↗

Wnt and planar cell polarity signaling in cystic renal diseaseSemantic proximity Read ↗

Primary cilium in kidney development, function and diseaseSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.