Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

CYP1B1 expression promotes the proangiogenic phenotype of endothelium through decreased intracellular oxidative stress and thrombospondin-2 expression.

Blood - 15 Jan 2009

Tang Yixin, Scheef Elizabeth A, Wang Shoujian, Sorenson Christine M, Marcus Craig B, Jefcoate Colin R, Sheibani Nader

Abstract excerpt

Reactive species derived from cell oxygenation processes play an important role in vascular homeostasis and the pathogenesis of many diseases including retinopathy of prematurity. We show that CYP1B1-deficient (CYP1B1(-/-)) mice fail to elicit a neovascular response during oxygen-induced ischemic...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Antioxidants
Share to Cytochrome P-450 CYP1B1
Share to Endothelium, Vascular

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to In Situ Nick-End Labeling

Share to Lipid Peroxidation

Share to Neovascularization, Pathologic

Share to Retinal Vessels

Share to Thrombospondins

Source

Open in PubMed Open full text

Identifiers

PMID: 19005183
DOI: 10.1182/blood-2008-03-145219
PMCID: PMC2628380

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-19005183-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

CYP1B1 expression promotes the proangiogenic phenotype of endothelium through decreased intracellular oxidative stress and thrombospondin-2 expression.PMID 19005183Read ↗

CYP1B1 and endothelial nitric oxide synthase combine to sustain proangiogenic functions of endothelial cells under hyperoxic stress.Semantic proximity Read ↗

Thrombospondin-1-deficient mice exhibit increased vascular density during retinal vascular development and are less sensitive to hyperoxia-mediated vessel obliteration.Semantic proximity Read ↗

Role of Cytochrome P450 2C Epoxygenases in Hypoxia-Induced Cell Migration and Angiogenesis in Retinal Endothelial CellsSemantic proximity Read ↗

PEDF expression affects retinal endothelial cell proangiogenic properties through alterations in cell adhesive mechanisms.Semantic proximity Read ↗

Heme oxygenase-1 deficiency accelerates formation of arterial thrombosis through oxidative damage to the endothelium, which is rescued by inhaled carbon monoxide.Semantic proximity Read ↗

Ultrastructural abnormalities of the trabecular meshwork extracellular matrix in Cyp1b1-deficient mice.Semantic proximity Read ↗

Attenuation of retinal endothelial cell migration and capillary morphogenesis in the absence of bcl-2.Semantic proximity Read ↗

Quantification of oxygen-induced retinopathy in the mouse: a model of vessel loss, vessel regrowth and pathological angiogenesisSemantic proximity Read ↗

Cytochrome P450 Oxidase 2C Inhibition Adds to ω-3 Long-Chain Polyunsaturated Fatty Acids Protection Against Retinal and Choroidal Neovascularization.Semantic proximity Read ↗

Differential sex-specific effects of oxygen toxicity in human umbilical vein endothelial cellsSemantic proximity Read ↗

Pharmacologic and Genetic Manipulation of MMP-2 and -9 Affects Retinal Neovascularization in Rodent Models of OIRSemantic proximity Read ↗

Kinetics of strain-dependent differential gene expression in oxygen-induced retinopathy in the rat.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.